Searchable abstracts of presentations at key conferences in endocrinology

ea0007p143 | Growth and development | BES2004

Pregnancy-induced plasticity in rat pituitary: a morphological and endocrine study of somatotroph and lactotroph function

El-Kasti M , Christian H , Huerta I , Hill N , Matthews D , Wells T

Pregnancy is associated with increased circulating growth hormone (GH), which is thought to originate from the placenta in humans, but from the pituitary in rats. In this study we investigated the changes in somatotroph and lactotroph populations, and quantified spontaneous and secretagogue-induced GH and prolactin (PRL) secretion during pregnancy in rats.Using electron microscopy and immunogold labelling, somatotroph and lactotroph populations were quan...